HIResist: Database of HIV-1 Resistance to Broadly Neutralizing Antibodies

Strain Sensitivity




   µg/ml



Resistance bnAbs: 89/171 (52%)


Antibody Assays gMean
0PV-a.01 1 100.000
0PV-b.01 1 100.000
0PV-c.01 1 100.000
10E8v4 2 1.607
17b 1 100.000
2408b 1 38.300
2408c.3 1 3.210
2413a 1 5.500
2413b 1 1.540
2413c 1 2.480
2F5 3 33.600
2G12 2 4.265
3074 1 100.000
35O22 1 49.000
447-52D 1 39.500
48d 1 100.000
4E10 4 40.331
8ANC195 2 100.000
A12V163-a.01 1 100.000
A12V163-a.02 1 100.000
A12V163-b.01 1 100.000
CAP256V2LS 1 100.000
CH01 1 100.000
CH12 1 100.000
DF1W-a.01 1 100.000
DF1W-a.02 1 100.000
DFPH-a.01 1 45.600
DFPH-a.03 1 38.600
DFPH-a.15 1 11.700
DH511.1 1 10.100
DH511.11P 1 3.950
DH511.12P 1 3.480
DH511.2 3 5.064
DH511.2_K3 1 1.710
DH511.3 1 22.900
DH511.4 1 21.900
DH511.5 1 17.400
DH511.6 1 22.900
DH517 1 100.000
F105 1 100.000
HJ16 1 100.000
J038 1 100.000
PG16 4 100.000
PG9 6 100.000
PG9-PG16-RSH 2 100.000
PG9RSH DU017 1 100.000
PG9RSH DU025 1 100.000
PG9RSH N(100f)Y 2 100.000
PGDM1400 5 100.000
PGDM1400-LS 1 100.000
PGT135 1 100.000
PGT145 1 48.400
PGT145 DU303 1 100.000
PGZL1 1 100.000
PGZL1.H4K3 1 100.000
PGZL1_gVmDmJ 1 100.000
VRC-PG04b 1 13.700
VRC-PG05 2 40.000
VRC06 1 4.700
VRC22.01 1 100.000
VRC23b 1 1.760
VRC26.08 1 100.000
VRC26.25 2 100.000
VRC26.25.K100mA 1 100.000
VRC26.26 1 100.000
VRC26.27 1 100.000
VRC34-UCA 1 100.000
VRC34.05 1 100.000
VRC38.01 1 4.430
VRC42.01 1 100.000
VRC42.02 1 100.000
VRC42.I3 1 100.000
VRC42.N1 1 10.400
VRC43.01 1 2.430
VRC46.01 1 100.000
Z13e1 1 100.000
polyclonal NIH45 1 75.000
vFP1.01 1 100.000
vFP16.02 2 218.632
vFP16.02 L-F60P 1 100.000
vFP16.02 L-S48K 1 442.000
vFP20.01 1 100.000
vFP48.02 1 100.000
vFP49.02 1 100.000
vFP5.01 1 100.000
vFP52.02 1 100.000
vFP53.02 1 100.000
vFP7.04 1 100.000
vFP7.05 1 100.000
Sensitivity bnAbs: 82/171 (48%)


Antibody Assays gMean
10-1074 2 0.088
10E8 6 0.841
10E8v4-5R-100cF 1 0.151
10E8v4-5R-100cF+N6 1 0.012
2411a 1 0.308
3BNC117 3 0.012
3BNC117_FR3-03 1 0.023
438-B11 1 0.223
7-269 1 0.122
ACS202 1 0.149
Bi-NAb 1 0.223
Bi-ScFv 1 0.062
CAP256.J3LS 1 0.087
CAP256V2LS-J3-3 1 0.033
CD4-Ig 2 0.967
CH103 2 0.068
CH235.12 1 0.296
IOMA 1 0.101
J3 1 0.067
N49P7 2 0.031
N49P7.v2 1 0.028
N6 2 0.014
N6-LS 1 0.013
N6-LS-N72Q-R18D 1 0.014
N6/10E8v4-PGDM1400 1 0.095
N6/PGDM1400-10E8v4 1 0.064
N6LS.C1 1 0.025
N6LS.C15 1 0.013
N6LS.C30 1 0.018
N6LS.C35 1 0.027
N6LS.C47 1 0.011
N6LS.C49 1 0.010
N6LS.C51 1 0.014
N6LS.C58 1 0.010
N6_FR3-03 1 0.015
NIH45-46 2 0.047
PGT121 6 0.099
PGT121.414.LS 1 0.068
PGT128 2 0.046
PGT151 5 0.026
Tri-NAb 1 0.156
VRC-CH30 1 0.102
VRC-CH31 1 0.039
VRC-CH32 1 0.053
VRC-CH33 1 0.036
VRC-CH34 1 0.147
VRC-PG04 2 0.587
VRC-PG19 1 0.274
VRC-PG20 1 0.060
VRC01 19 0.106
VRC01-LS 1 0.086
VRC01.23LS 1 0.008
VRC01/PGDM1400-10E8v4 1 0.570
VRC01_FR3-03 1 0.027
VRC02 1 0.075
VRC03 3 0.026
VRC06b 1 0.025
VRC07 2 0.015
VRC07-501-LS 1 0.006
VRC07-508-LS 1 0.003
VRC07-523-F54-LS.v3 1 0.008
VRC07-523-LS 4 0.010
VRC07-523-LS-N72Q-R24D 1 0.018
VRC07-523-LS_FR3-03 1 0.010
VRC07-523-W54-LS.v3 1 0.006
VRC07-523LS.v1 1 0.008
VRC07-523LS.v11 1 0.005
VRC07-523LS.v14 1 0.005
VRC07-523LS.v32 1 0.006
VRC07-523LS.v34 1 0.007
VRC07-544-LS 1 0.006
VRC07_FR3-03 1 0.016
VRC08 1 0.018
VRC13 1 0.028
VRC16 1 0.055
VRC23 2 0.157
VRC29.03 1 0.547
VRC34-pI3 1 0.982
VRC34-pI4 1 0.994
VRC34.01 3 0.488
b12 4 0.082
gVRC-H1dC38/VRC01L 1 0.132